My main thought was to use Godot for more complex and advance applications, which are highly interactive and visual in nature.
I admit I don't know the needs of those who use accessibility features that well, but I would assume that these are not the kinds of applications people with significant disability would want to use anyway.
E.g. if you are blind, I cannot see how you can use a very complex interface. Yes you can fill out government forms on the web, but say using a 3D modeling application is quite another matter.
Likewise if you don't have access to your arms to move a mouse I don't think you would want to use a highly visual and mouse interactive tool to begin with.
In fact I would assume command line based tools would be preferable.
But as I said, I am just speculating. I don't know what their world is like. But I highly doubt that the people using these other frameworks do very much at all to aid people with special needs.
In all my life as a software developer I have not seen anyone pay attention to them. I work as a software developer in Norway.
And most of the time we haven't even bothered to make the software accessible to people who are only speaking Norwegian. In other words if we aren't even catering to our own language, there is slim hope for attention to other groups of people with special needs.